GLP Contract Research Services
OUR SERVICES
THE COMET ASSAY EXPERTS TAKE RESEARCH TO REGULATORY SUBMISSION
WHAT WE DO.
Helix3 customizes experimental designs and conducts all services according to the GLPs. This minimizes the risk of false positive or unclear results while ensuring the dependability and reproducibility of the methods conducted. As the acknowledged Comet Assay expert responsible for advancing Comet from a research tool to international regulatory acceptance, Helix3 has the expertise to help you with any of your research or regulatory submission needs.
REGULATED STUDIES
In Vivo Comet Assay
Conducted in any species/strain on any tissue:
Liver Stomach Adrenals Sperm
Kidney Duodenum Hypothalamus Ovary
Spleen Colon Thyroid Prostate
Blood Cecum Pituitary Mammary
Lung Ileum Pineal Uterus
B.Marrow Bladder Pancreas Testis
Combined In Vivo Comet and Micronucleus Assay
Any comet tissue(s) and micronucleus evaluation of the bone marrow or peripheral blood from the same exposure unit
GLP RESEARCH SERVICES
Method Development
In vitro, in vivo, ex vivo and/or clinical methods modified and optimized to accommodate specific exposure, application, or regulatory agency requirements
Screening Studies
In vitro DNA Reactivity Screening
In vivo target organ toxicity tests
Conducted to identify the best testing or development approach and to minimize the risk of unexpected positive safety testing results
Mobile Comet Assay
Conducted onsite at any client-specified facility, clinic or field site where our expertise is required to collect and process comet samples from any ongoing experiment, species or exposure condition
Investigative Studies
Weight-of-evidence (WoE) or mechanistic studies designed and conducted to answer a specific question or to further support a regulatory submission
Study Evaluation and Validation
Evaluation of previously conducted studies or experiments to determine the validity of the data, identify optimization opportunities, and make recommendations for development progression
Experimental Design and Troubleshooting
Customized protocol development, troubleshooting, and method testing to achieve specific research or regulatory objectives