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OUR SERVICES

THE COMET ASSAY EXPERTS TAKE RESEARCH TO REGULATORY SUBMISSION

WHAT WE DO

Helix3 customizes experimental designs and conducts all services according to the GLPs.  This minimizes the risk of false positive or unclear results while ensuring the dependability and reproducibility of the methods conducted.  As the acknowledged Comet Assay expert responsible for advancing Comet from a research tool to international regulatory acceptance, Helix3 has the expertise to help you with any of your research or regulatory submission needs.

REGULATED STUDIES

In Vivo Comet Assay

 

Conducted in any species/strain on any tissue:

 

Liver         Stomach     Adrenals               Brain

Kidney     Duodenum  Hypothalamus  Ovary

Spleen     Colon            Thyroid                 Prostate

Blood        Cecum         Pituitary              Mammary

Lung          Ileum           Pineal Gland       Uterus

B.Marrow Bladder      Pancreas            Testis

Combined In Vivo Comet and Micronucleus Assay

 

Any comet tissue(s) and micronucleus evaluation of the bone marrow or peripheral blood from the same exposure unit

More

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GLP RESEARCH SERVICES

Method Development

 

In vitro, in vivo, and ex vivo  methods modified and optimized to accommodate specific exposure, application, or regulatory requirements

Screening Studies

 

 DNA Reactivity Screening

To determine direct DNA reactivity of any test compound

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Target Organ Toxicity Tests

​To minimize the risk of false positive in vivo genotoxicity test results

Mobile Comet Assay

 

Conducted onsite at any client-specified facility, clinic or field site where our expertise is required to collect and process fresh comet samples from any ongoing experiment, species or exposure condition

Investigative Studies

 

Weight-of-evidence (WoE) or mechanistic studies designed and conducted to answer a specific question or to further support a regulatory submission

Study Review and Evaluation

 

Evaluation of previously conducted studies or experiments to determine the validity of the data,  identify optimization opportunities, and make recommendations for development progression

Experimental Design and Troubleshooting

 

Customized method development, troubleshooting, and validation to achieve specific research or regulatory objectives

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